MRS-2578 is a selective antagonist of P2Y6 nucleotide receptors (IC50 values are 37 and 98 nM at human and rat P2Y6 receptors respectively)
reduces serum follicle stimulating hormone and testosterone level
In Phase 2 study treatment with nepicastat was not effective in relieving PTSD-associated symptoms when compared to placebo
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4'-Demethylpodophyllotoxin mnacanthal MRS-2578 is a selective antagonist4' Demethylpodophyllotoxin is an aryltetralin lignin contained in the root of Podophyllum hexandrum and P. peltatum. 4' Demethylpodophyllotoxin exhibits cytotoxic potential in diverse cancer cell lines. Product information CAS Number: 40505 27 9 Molecular Weight: 400. 38 Formula: C21H20O8 Chemical Name: (10R,11R,15R,16R) 16 hydroxy 10 (4 hydroxy 3,5 dimethoxyphenyl) 4,6,13 trioxatetracyclo[7. 7. 0. 0,. 0,]hexadeca 1,3(7),8 trien 12 one Smiles: