Glafenine 15959 selective and cell-permeable p300/CBP histone

selective and cell-permeable p300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 ~400 nM

InChi: InChI=1S/C21H22O11/c22-8-15-18(28)19(29)20(30)21(32-15)31-14-6-3-10(16(26)17(14)27)11(23)4-1-9-2-5-12(24)13(25)7-9/h1-7

Smiles: C[C@@H](CC)[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CC1C=CC(O)=CC=1)C(O)=O

GSK 923295

CI-1033 shows excellent potency for irreversible inhibition of erbB2 autophosphorylation in MDA-MB 453 cells

Glafenine 15959 selective and cell-permeable p300/CBP histoneGlafenine is a non steroidal anti inflammatory drug (NSAID), is a non narcotic analgesic agent, widely used for the treatment of pains of various origins. Product information CAS Number: 3820 67 5 Molecular Weight: 372. 80 Formula: C19H17ClN2O4 Chemical Name: 2,3 dihydroxypropyl 2 [(7 chloroquinolin 4 yl)amino]benzoate Smiles: OCC(O)COC(=O)C1=CC=CC=C1NC1=CC=NC2=CC(Cl)=CC=C21 InChiKey: GWOFUCIGLDBNKM UHFFFAOYSA N InChi: InChI=1S C19H17ClN2O4 c20 12 5 6