KO-947 3-amine Chemical Name: N-(4-ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-((tetrahydro-2H-pyran-4-yl)methoxy)benzenesulfonamide

Chemical Name: N-(4-ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-((tetrahydro-2H-pyran-4-yl)methoxy)benzenesulfonamide

and shows minor toxicity by the oral route when administered as Cloperastine fendizoate

Chemical Name: N-(2-((S)-3-(((1r

K02288 specifically inhibited the BMP-induced Smad pathway without affecting TGF-β signaling and induced dorsalization of zebrafish embryos

and does not potently inhibit PI3K

KO-947 3-amine Chemical Name: N-(4-ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-((tetrahydro-2H-pyran-4-yl)methoxy)benzenesulfonamideKO 947 is a potent and selective inhibitor of ERK1 2 kinases. KO 947 blocks ERK signaling and proliferation of tumor cells exhibiting dysregulation of MAPK pathway signaling at low nanomolar concentrations. Product information CAS Number: 1695533 89 1 Molecular Weight: 355. 39 Formula: C21H17N5O Chemical Name: 1,5,6,8 Tetrahydro 6 (phenylmethyl) 3 (4 pyridinyl) 7H pyrazolo[4,3 g]quinazolin 7 one Smiles: