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at or below the maximum tolerated dose
Smiles: O=S1(=O)N=C(NC2=CC=CC=C2N2CCCC2)C2=CC=CC=C12
Chemical Name: (R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3
InChi: InChI=1S/C25H25F3N4O6/c1-24(15-31-14-22(32(33)34)29-23(31)38-24)16-35-18-4-2-17(3-5-18)30-12-10-20(11-13-30)36-19-6-8-21(9-7-19)37-25(26
AEE788 also inhibits the phosphorylation of KDR in CHO cells and erbB2 in BT-474 cells
Asenapine 0289 at or below the maximumAsenapine, also known as Org 5222 and HSDB 8061, shows high affinity (pKi) for numerous receptors, including the serotonin 5 HT1A (8. 6), 5 HT1B (8. 4), 5 HT2A (10. 2), 5 HT2B (9. 8), 5 HT2C (10. 5), 5 HT5A (8. 8), 5 HT6 (9. 5), and 5 HT7 (9. 9) receptors, the adrenergic 1 (8. 9), 2A (8. 9), 2B (9. 5), and 2C (8. 9) receptors, the dopamine D1 (8. 9), D2 (8. 9), D3 (9. 4), and D4 (9. 0) receptors, and the histamine H1 (9. 0) and H2 (8. 2) receptors.
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