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13)14/h3-5
11b-octadecahydro-3'H-spiro[cyclohexa[a]fluorene-9
Smiles: CN(CCCN1CCC2=CC(OC)=C(C=C2CC1=O)OC)CCC1=CC(OC)=C(C=C1)OC
whereas 12
InChi: InChI=1S/C22H34ClN3O2/c1-17(2)26(18(3)27)16-12-22(21(24)28
PHT-7.3 l-PEG4-Val-Cit-PAB-OH 13)14/h3-5PHT 7. 3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain (Kd=4. 7 M). PHT 7. 3 inhibits mut KRas, but not wild type KRas cancer cell and tumor growth and signaling. PHT 7. 3 has antitumor activity. Product information CAS Number: 1614225 93 2 Molecular Weight: 433. 52 Formula: C24H23N3O3S Chemical Name: 4 [(1,3 dioxan 2 yl)methyl] 2 {[4 (4 methylphenyl) 1,3 thiazol 2 yl]methyl} 1,2
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