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ATR inhibitor 2 oxamide Tromethamine 3-dimethylbutanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide

SKU: 77488946225

4.8
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Description

3-dimethylbutanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide

Arctiin and arctigenin have shown anticancer effects

CCCCCCCCCCCC1(C)OC(COCCCS([O-])(=O)=O)CO1

CAS Number: 105816-04-4

Smiles: O=C(COC1C=CC(Cl)=CC=1)NC1CCC(CC1)NC(=O)COC1C=CC(Cl)=CC=1

ATR inhibitor 2 oxamide Tromethamine 3-dimethylbutanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamideATR inhibitor 2 is an ATP competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. ATR inhibitor 2 potently inhibits ATR driven phosphorylated checkpoint kinase 1 (Chk1) phosphorylation with an IC50 of 8 nM. Antitumor activity. Product information CAS Number: 1613191 99 3 Molecular Weight: 541. 55 Formula: C25H29F2N9O3 Chemical Name: 2 amino 6 fluoro N (5 fluoro 4 {4 [4 (oxetan 3 yl)piperazine 1 carbonyl]piperidin 1 yl}pyridin 3

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