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Smiles: CN(CC1C=CC(=CC=1)C1NC2C=C(F)C=C3C=2C=1CCNC3=O)CCOCCOCCOCCOCCOCCOCCNC1=CC=CC2C(=O)N(C3CCC(=O)NC3=O)C(=O)C1=2
The most unique feature is the relative terminal long half-life of about 26 hours
4μ8c (IRE1 Inhibitor III) (i
at the maximum doses investigated
From 4 to 8 hours the drug plasma levels drops to 0
BAY-85-8501 osuccinimidyl oleate Smiles: CN(CC1C=CC(=CC=1)C1NC2C=C(F)C=C3C=2C=1CCNC3=O)CCOCCOCCOCCOCCOCCOCCNC1=CC=CC2C(=O)N(C3CCC(=O)NC3=O)C(=O)C1=2BAY 85 8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM. Product information CAS Number: 1161921 82 9 Molecular Weight: 474. 46 Formula: C22H17F3N4O3S Chemical Name: (4S) 4 (4 cyano 2 methanesulfonylphenyl) 3,6 dimethyl 2 oxo 1 [3 (trifluoromethyl)phenyl] 1,2,3,4 tetrahydropyrimidine 5 carbonitrile Smiles: CN1[C@@H](C(C#N)=C(C)N(C1=O)C1C=C(C=CC=1)C(F)(F)F)C1=CC=C(C=C1S(C)(=O)=O)C#N