ALK-IN-9 inostat Smiles: OC(CN1C2=CC=C(Cl)C=C2C2=CC(Cl)=CC=C12)CN1C(=O)SCC1=O

Smiles: OC(CN1C2=CC=C(Cl)C=C2C2=CC(Cl)=CC=C12)CN1C(=O)SCC1=O

and has potent analgesia and anti-inflammary effects

Smiles: CN(CCO)CC[C@H](CSC1C=CC=CC=1)NC1=CC=C(C=C1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)C1=CC=C(C=C1)N1CCC(CC1)[C@@H](O)C1=CC=CC=C1C1C=CC(Cl)=CC=1

MCF-7 (IC50=82

8-dihydroxy-3a

ALK-IN-9 inostat Smiles: OC(CN1C2=CC=C(Cl)C=C2C2=CC(Cl)=CC=C12)CN1C(=O)SCC1=OALK IN 9 (compound 40) is a potent ALK inhibitor. ALK IN 9 inhibits cell proliferation with IC50s of <0. 2 nM, <0. 2 nM, 0. 2 nM for Ba F3 EML4 ALK, KM 12 (TPM3 TRKA), KG l cell (OP2 FGFR1), respectively. Product information CAS Number: 2359662 39 6 Molecular Weight: 412. 42 Formula: C20H21FN6O3 Chemical Name: (18R) 13 fluoro 7,7,18 trimethyl 9,20 dioxa 1,2,6,11,17,23 hexaazapentacyclo[19. 3. 1. 0,. 0,. 0,]pentacosa 2,4(24),10,12,14,21(25),22 heptaen