TAK-960 monohydrochloride 9-4603 Censavudine is a potent HIV

Censavudine is a potent HIV inhibitor with EC50 ranges from 30 nM to 81 nM and 450 nM to 890 nM for HIV-2 and HIV-1

Chemical Name: 1-{2-oxo-2-[3'-(trifluoromethyl)-[1

US20060281100A1)

InChiKey: ZJRPDIPXWGIHRB-SBCNVUAESA-N

740 Y-P (30 μM

TAK-960 monohydrochloride 9-4603 Censavudine is a potent HIVTAK 960 monohydrochloride is an orally available, selective inhibitor of polo like kinase 1 (PLK1), with an IC50 of 0. 8 nM. TAK 960 monohydrochloride also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16. 9 and 50. 2 nM, respectively. TAK 960 monohydrochloride inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts. Product information CAS Number: 2108449 45 0