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GNE684 also had no impact on overall survival or tumor growth in the KPP or KPR (LSL-Kras G12D/+
a proteolysis peptide
InChiKey: MRDBGMJEPGXQHJ-UHFFFAOYSA-N
Smiles: CS(=O)(=O)N[C@@H]1CC[C@@H](CN2CCC3(CN(C3)C3=NC=NC=C3OC3=CC=C(F)C=C3C(=O)N(C(C)C)C(C)C)CC2)CC1
quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata
IDO-IN-8 16729 GNE684 also had no impactIDO IN 8 (NLG 1487) is an indoleamine 2,3 dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1487, has an IC50 of 1 10 M. Product information CAS Number: 1402837 77 7 Molecular Weight: 316. 37 Formula: C18H21FN2O2 Chemical Name: (1S,4r) 4 [(1S) 2 [(5R) 6 fluoro 5H imidazo[4,3 a]isoindol 5 yl] 1 hydroxyethyl]cyclohexan 1 ol Smiles: O[C@@H]1CC[C@H](CC1)[C@@H](O)C[C@@H]1C2C(F)=CC=CC=2C2=CN=CN21 InChiKey: YGACXVRLDHEXKY
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