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Antibody-PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4
InChiKey: XDOFWFNMYJRHEW-UHFFFAOYSA-N
Smiles: C[C@@H](O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@@H](N)CO)C(C)C)C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(O)=O
InChi: InChI=1S/C27H44O7/c1-23(2
CC1=CN=C(O)N(CCCN2CCN(CC2)C2=CC=CC=C2OCC(F)(F)F)C1=O
(Rac)-3′-Hydroxy simvastatin Size:Contact [email protected] for quotation Antibody-PROTAC Conjugates Enable HER2-Dependent Targeted(Rac) 3 Hydroxy simvastatin is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG CoA reductase with a Ki of 0. 2 nM. Product information CAS Number: 126313 98 2 Molecular Weight: 434. 57 Formula: C25H38O6 Chemical Name: 8 [2 (4 hydroxy 6 oxooxan 2 yl)ethyl] 3,7 dimethyl 1,2,3,7,8,8a hexahydronaphthalen 1 yl 3 hydroxy 2,2 dimethylbutanoate Smiles: CC(O)C(C)(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C21 InChiKey: