TPA 023 Catalog No.:M21822-C InChi: InChI=1S/C26H32O13/c1-33-14-5-3-12(9-15(14)34-2)4-6-17(28)36-11-26-18-13(19(29)23(26)39-26)7-8-35-24(18)38-25-22(32)21(31)20(30)16(10-27)37-25/h3-9

Name: TPA 023 Catalog No.:M21822-C InChi: InChI=1S/C26H32O13/c1-33-14-5-3-12(9-15(14)34-2)4-6-17(28)36-11-26-18-13(19(29)23(26)39-26)7-8-35-24(18)38-25-22(32)21(31)20(30)16(10-27)37-25/h3-9
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Description

InChi: InChI=1S/C26H32O13/c1-33-14-5-3-12(9-15(14)34-2)4-6-17(28)36-11-26-18-13(19(29)23(26)39-26)7-8-35-24(18)38-25-22(32)21(31)20(30)16(10-27)37-25/h3-9

InChiKey: VNLPYEMGHGDRRZ-MRVPVSSYSA-N

KI-20227 suppresses experimental autoimmune encephalomyelitis

Phase I pharmacokinetic/pharmacodynamic study of MLN8237

Formula: C66H76Cl3N9O24

TPA 023 Catalog No.:M21822-C InChi: InChI=1S/C26H32O13/c1-33-14-5-3-12(9-15(14)34-2)4-6-17(28)36-11-26-18-13(19(29)23(26)39-26)7-8-35-24(18)38-25-22(32)21(31)20(30)16(10-27)37-25/h3-9TPA 023 is a GABAA 2 3 subtype selective agonist, with Ki of 0. 19 0. 41 nM. Product information CAS Number: 252977 51 8 Molecular Weight: 395. 43 Formula: C20H22FN7O Chemical Name: 5 ({[7 tert butyl 3 (2 fluorophenyl) [1,2,4]triazolo[4,3 b]pyridazin 6 yl]oxy}methyl) 1 ethyl 1H 1,2,4 triazole Smiles: CCN1N=CN=C1COC1=NN2C(=NN=C2C=C1C(C)(C)C)C1=CC=CC=C1F InChiKey: QKIWQBLNTSQOLY UHFFFAOYSA N InChi: InChI=1S C20H22FN7O c1 5 27 17(22 12 23 27)11 29 19

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