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Glucosylceramide synthase inhibitor PDMP sensitizes chronic myeloid leukemia T315I mutant to Bcr-Abl inhibitor and cooperatively induces glycogen synthase kinase-3-regulated apoptosis
Smiles: CC1=CC=C(N)C=C1C(=O)N[C@H](C)C1=CC=CC2=CC=CC=C21
A small molecule that blocks fat synthesis by inhibiting the activation of SREBP
H2O/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52
The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines
Olmutinib free base - CAS# 1353550-13-6 size:2mg solid Glucosylceramide synthase inhibitor PDMP sensitizesOlmutinib free base, CAS No. 1353550 13 6, also known as HM61713 and BI 1482694, is a potent small molecule inhibitor of Bruton's tyrosine kinase (BTK). BTK is a member of the Tec family of non receptor protein tyrosine kinases. BTK is mostly expressed in hematopoietic cells such as B cells, mast cells and macrophages. BTK plays key roles in multiple cell signaling pathways including B Cell Receptor (BCR) and Fc receptor (FcR) signaling cascades and
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