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62(5):951-6
Formula: C26H43Cl3N4
It shows antiproliferative activity in a range of cancer cell lines (IC50 ~ 3 - 21 nM)
A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas
rat (4 mg/kg
Dexpramipexole dihydrochloride Size:Solid 10 mg 62(5):951-6Dexpramipexole, also known as KNS 760704 and (R) Pramipexole, is under development for the treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrigs disease. The drug failed to show efficacy in terms of function or survival in a Phase III study of patients with ALS. Dexpramipexole is a low molecular weight, water soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics, and has been shown to be well
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US$ 4035.00