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UNC6852 selectively degrades EED and EZH2
GW3965 HCl
and also inhibits murine ROCK-2 or rat ROCK-2 with IC50s of 2
C[C@@H]1N[C@@H]2CCCCCCCC(=O)O[C@H]3CC[C@@H](CCCCCCCC(=O)O[C@H]1CC2)N[C@H]3C
Erratum in: J Org Chem
Lenalidomide-5-aminomethyl mopan dihydrate UNC6852 selectively degrades EED andLenalidomide 5 aminomethyl is the Lenalidomide based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide 5 aminomethyl can be connected to the ligand for protein by a linker to form PROTAC. Product information CAS Number: 1010100 28 3 Molecular Weight: 273. 29 Formula: C14H15N3O3 Chemical Name: 3 [5 (aminomethyl) 1 oxo 2,3 dihydro 1H isoindol 2 yl]piperidine 2,6 dione Smiles: NCC1=CC2CN(C3CCC(=O)NC3=O)C(=O)C=2C=C1 InChiKey:
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