CDDO-dhTFEA Catalog No.:M28476-C 37)38)22(33)25(35)30-10-8-29(9-11-30)24(34)17-6-4-3-5-7-17

37)38)22(33)25(35)30-10-8-29(9-11-30)24(34)17-6-4-3-5-7-17

SU-14813 maleate

Smiles: NC1C=CC(=CC=1)C(=O)N(CCN1CCC(CC1)C(=O)C1C=CC=CC=1)C1C=NC=CC=1

In the strategy

SH-SY5Y cells) attenuates the paraquat-induced accumulation of reactive oxygen species (ROS) and attenuates the paraquat-induced expression of apoptotic proteins

CDDO-dhTFEA Catalog No.:M28476-C 37)38)22(33)25(35)30-10-8-29(9-11-30)24(34)17-6-4-3-5-7-17CDDO dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro inflammatory transcription factor NF B. CDDO dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF B and transforming growth factor pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats. Product