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Hydroxy-Dynasore Catalog No.:M25683-C JAK2 and JAK3 with IC50

SKU: 82210869339

4.3
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Description

JAK2 and JAK3 with IC50 of 0

once daily) significantly reduces the volume of tumor in mice bearing H1993 tumors

CBP/p300 ligand 2 is a ligand for target protein for PROTAC of dCBP-1

InChi: InChI=1S/C56H78N16O13/c1-5-31(4)46(71-50(79)40(22-33-15-17-36(73)18-16-33)67-52(81)45(30(2)3)70-48(77)38(13-9-19-62-56(58)59)65-47(76)37(57)25-44(74)75)53(82)68-41(23-34-26-60-28-63-34)54(83)72-20-10-14-43(72)51(80)66-39(21-32-11-7-6-8-12-32)49(78)69-42(55(84)85)24-35-27-61-29-64-35/h6-8

InChi: InChI=1S/C25H31F3N4O2/c1-32(2)13-12-29-24(33)30-15-18-9-10-19-22(16-6-4-3-5-7-16)31-21-11-8-17(25(26

Hydroxy-Dynasore Catalog No.:M25683-C JAK2 and JAK3 with IC50Hydroxy Dynasore (Dyngo 4a), a structural analog of Dynasore (HY 15304), is an potency improved, low cytotoxicity and nonspecific binding dynamin inhibitor with IC50 values of 0. 38 M and 2. 3 M for brain dynamin I and recombinant rat dynamin II, respectively. Hydroxy Dynasore inhibits dynamindependent endocytosis of transferrin with an IC50 of 5. 7 M in vitro. Product information CAS Number: 1256493 34 1 Molecular Weight: 338. 31 Formula: C18H14N2O5

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