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Target: dopamine D2 receptor
CAS Number: 612487-72-6
019 μM) as a VEGFR-targeted inhibitor and powerfully suppresses the proliferation of MET-amplified cancer cells (GI50=0
Smiles: CN1CCN(CC1)C1=CC2=C(C=C1F)C(=O)C(=CN2CC)C(O)=O
InChi: InChI=1S/C14H10N4O/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10/h2-6
CPI-1189 Catalog No.:M23038-C Target: dopamine D2 receptorCPI 1189 is a proapoptotic cytokine tumor necrosis factor (TNF) alpha inhibitor. AIDS dementia complex is characterized by increased gliosis, apoptosis, and oxidative stress in the CNS, as well as a compromised blood brain barrier. TNF alpha has been reported to be elevated in AIDS dementia complex brains and may contribute to AIDS dementia complex. In vitro: CPI 1189 could potently inhibit p38 MAPK phosphorylation displaying protective action against
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