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InChiKey: JJVJQVAFUFUTGS-UHFFFAOYSA-N
a BET bromodomain inhibitor now in clinical development
5-a]pyrimidin-7-yl]amino}piperidine-1-carboxylate
Formula: C48H47N4O10P
1 μM in A2780 and TOV-21G ovarian cancer and MDA-MD-231 breast cancer cells
MDL 72832 hydrochloride Catalog No.:M22802-C InChiKey: JJVJQVAFUFUTGS-UHFFFAOYSA-NMDL 72832 hydrochloride is a potent and selective ligand for 5 HT1A receptor with pIC50 value of 9. 1 . The 5 HT1A receptor is a G protein coupled receptor for endogenous neurotransmitter serotonin (5 HT) and mediates inhibitory neurotransmission. MDL 72832 hydrochloride is a potent and selective ligand for 5 HT1A receptor . Also, MDL 72832 exhibited affinity with pKD values of 6. 32 and 6. 34 for 5 HT1C and 5 HT1D receptors, respectively . In rats,
US$ 140.10
US$ 70.00