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Molecular Weight: 339
66428-89-5
BMS-708163 was dosed orally in female rats at 10 and 100 mg/kg once per day
PF-04979064
InChi: InChI=1S/C24H32N6O3/c1-3-25-24(31)26-18-6-4-17(5-7-18)22-27-21-12-29(19-14-33-15-19)9-8-20(21)23(28-22)30-10-11-32-13-16(30)2/h4-7
ORY-1001 (RG-6016) - LSD1 Inhibitor. CAS# 1431326-61-2 430 Molecular Weight: 339ORY 1001, CAS No. 1431326 61 2, is a highly potent and selective inhibitor of Lysine Specific Demethylase 1 (LSD1) with IC50 <20 nM. It is highly selective over related enzymes such as MAO A B. ORY 1001 affects AML stem cells, a sub population of cancer cells that has been proposed to be responsible for frequent relapses of the disease. It significantly reduces tumor cell load and increases survival time in mouse models of Acute Lymphoblastic
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