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Formula: C17H10Cl2F3N5O
23-9-10-23)24-11-12-24)16-7-8-19(25(27)28)20(14-16)30-18-6-4-5-17(13-18)21(26)22(2)3/h4-8
InChi: InChI=1S/C14H23NO
used as a component of eye drops for myopic control
Genetic inactivation or depletion of the TRiC complex results in human HSF1 activation and HSF1A inhibits the direct interaction between purified TRiC and HSF1 in vitro
SB 202190 hydrochloride 15811 Formula: C17H10Cl2F3N5OSB 202190 hydrochloride is an inhibitor of p38 MAP kinases, inhibiting p38 (SAPK2A, MAPK14) and p38 (SAPK2B, MAPK11). It directly binds to the ATP binding pocket of p38 MAP kinases and has been used to elucidate the roles of p38 MAP kinases in inflammatory cytokine expression, nicotine induced receptor expression, and HIV mediated depressive disorder. SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for
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