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Formula: C12H11N3O
CAS Number: 658084-23-2
PF-2545920
in the cells
PubMed PMID: 23441761
(+)MK-801 maleate - CAS# 77086-22-7 0012 Formula: C12H11N3O(+)MK 801 maleate, CAS No. 77086 22 7, is an uncompetitive antagonist of the N Methyl D aspartate (NMDA) receptor. Dizocilpine blocks NMDA receptors in a use and voltage dependent manner, since the channel must open for the drug to bind inside it. The drug acts as a potent anti convulsant and likely has dissociative anesthetic properties, but it is not used clinically for this purpose due to the discovery of brain lesions, called Olney's lesions (see
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