Reversine Catalog No.:M10364-10 Smiles: CC1NC2=CC=C(F)C=C2C=1C1NC2=C(N=1)C1=CC=CN=C1C1=NC=CC=C21

Smiles: CC1NC2=CC=C(F)C=C2C=1C1NC2=C(N=1)C1=CC=CN=C1C1=NC=CC=C21

25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12)13-4-11(18)2-3-14(13)19/h2-4

Smiles: OCCOCCN1CCN(CC1)C1=NC2=CC=CC=C2SC2=CC=CC=C21

CAS Number: 543730-41-2

CCCCC1OC2=CC=CC=C2C=1C(=O)C1=CC(I)=C(OCCN(CC)CC)C(I)=C1

Reversine Catalog No.:M10364-10 Smiles: CC1NC2=CC=C(F)C=C2C=1C1NC2=C(N=1)C1=CC=CN=C1C1=NC=CC=C21Reversine is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation. Reversine is also a novel Aurora kinases inhibitor that inhibits colony formation of human acute myeloid leukemia cells. Reversine inhibits the phosphorylation of histone H3, a direct downstream target of Aurora kinases. Similarly to the Aurora kinase inhibitor VX 680, reversine inhibited colony formation of leukemic cells from patients with