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this agent is highly polyglutamylated and competes for the folate binding site of DHFR
5-3(6)1-2-4(7)8/h3-8H
binds to and inhibits the activity of CDKs
CAS Number: 19046-60-7
28(20):3356-3362
USP25/28 inhibitor AZ1 oid-binding protein(668-687) TFA this agent is highly polyglutamylatedUSP25 28 inhibitor AZ1 (AZ1) is an orally active, selective, noncompetitive, dual ubiquitin specific protease (USP) 25 28 inhibitor with IC50s of 0. 7 M and 0. 6 M, respectively. USP25 28 inhibitor AZ1 attenuates colitis and tumorigenesis in the mice model. Product information CAS Number: 2165322 94 9 Molecular Weight: 422. 21 Formula: C17H16BrF4NO2 Chemical Name: 2 {[(5 bromo 2 {[4 fluoro 3 (trifluoromethyl)phenyl]methoxy}phenyl)methyl]amino}ethan 1
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