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Smiles: CC(=O)C1=CC2=C(O1)C(=O)C1=CC=CC=C1C2=O
PubMed Central PMCID: PMC3064743
2011 Nov-Dec
is sufficient to inhibit PC-3 tumor growth in vivo
InChiKey: IHLAQQPQKRMGSS-SCSAIBSYSA-N
Foretinib 603oglibose Smiles: CC(=O)C1=CC2=C(O1)C(=O)C1=CC=CC=C1C2=OForetinib, also known as XL880 and GSK1363089, is an orally bioavailable small molecule with potential antineoplastic activity. MET VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c MET and vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of tumor angiogenesis, tumor cell proliferation and metastasis. The proto oncogene c MET has been found to be over
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