Azidothymidine (AZT) - Reverse Transcriptase Inhibitor. CAS# 30516-87-1 Catalog No.:M60238-2S and cynomolgus monkeys after oral

and cynomolgus monkeys after oral administration

This causes global changes in protein acetylation and gene expression

with IC50s of 18

In rabbit isolated ventricular myocytes

CAS Number: 919973-83-4

Azidothymidine (AZT) - Reverse Transcriptase Inhibitor. CAS# 30516-87-1 Catalog No.:M60238-2S and cynomolgus monkeys after oralAzidothymidine (AZT), CAS No. 30516 87 1, is a selective, orally bioavailable and brain penetrant reverse transcriptase inhibitor. It has 100 fold selectivity for HIV reverse transcriptase over DNA polymerase . It can suppress HIV 1 replication and enhance cell viability in a HIV 1 infected T cell line. It can also suppress growth of a multiple myeloma (MM) cell line and reduces the growth of MM tumor xenografts in mice. In recent studies, AZT can