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PIK-III is at least 100-fold-selective for VPS34 over related lipid kinases such as PI3K and the protein kinase mTOR
288(37):26944-54
Solubility: DMSO 77 mg/mL (199
59(12):3099-107
Smiles: CC(C)(O)C(O)CC1C(OC)=C2C=CC(=O)OC2=CC=1OC
N-Desmethyltamoxifen Catalog No.:M14339-2 PIK-III is at least 100-fold-selectiveN Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N Desmethyltamoxifen, a poor antiestrogen, is a ten fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation. Product information CAS Number: 31750 48 8 Molecular Weight: 357. 49 Formula: C25H27NO Chemical
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