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IC50 value:Target: K-ras G12C inhibitorFor more information
Chakrabarti G
is a potent and Selective GLUT1 Inhibitor
approximately 58-fold more effective than sodium stibogluconate
is a selective inhibitor of transforming growth factor-β type I receptor (ALK5
Ruxolitinib (S) 05 trifluoroacetate IC50 value:Target: K-ras G12C inhibitorForS Ruxolitinib is a less active enantiomer of Ruxolitinib, a JAK1 2 inhibitor. S Ruxolitinib was initially developed to target the constitutive activation of the JAK STAT pathway. Janus kinases (JAKs) are a family of cytoplasmic tyrosine kinases that mediates signals from the receptors for various cytokines and growth factors that have a key role in haematopoiesis and immune function. Ruxolitinib maintains its anti JAK activity by competitive
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