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Epub 2015 Mar 28
the level of CD22 has decreased relative to that on G5/44-treated cells and continued to decrease
InChi: InChI=1S/C27H21N5O2/c1-3-25(33)31-11-10-17-4-7-21(13-24(17)31)32-26(34)9-6-19-14-28-23-8-5-18(12-22(23)27(19)32)20-15-29-30(2)16-20/h3-9
OSU-03012 remarkably decreases expression of EGFR protein in the tumors by 48% compared with vehicle controls and also prevents YB-1 from binding to the EGFR promoter in MDA-MB-435/LCC6 xenografts
Formula: C48H76O18
Tirbanibulin Mesylate yl-β-D-glucuronide Epub 2015 Mar 28Tirbanibulin Mesylate (KX2 391 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src, with GI50 of 9 60 nM in cancer cell lines. Product information CAS Number: 1080645 95 9 Molecular Weight: 527. 63 Formula: C27H33N3O6S Chemical Name: N benzyl 2 (5 (4 (2 morpholinoethoxy)phenyl)pyridin 2 yl)acetamide methanesulfonate Smiles: CS(O)(=O)=O. O=C(CC1C=CC(=CN=1)C1C=CC(=CC=1)OCCN1CCOCC1)NCC1C=CC=CC=1 InChiKey: JGSYRKUPDSSTCB
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