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PF-4708671 specifically inhibits the S6K1 isoform with a Ki of 20 nM and IC50 of 160 nM
Epub 2013 Dec 19
Chemical Name: 2-(5-chloro-2-{[3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)-N-cyclopropyl-1-benzothiophene-4-carboxamide trihydrochloride
Smiles: CC1=CC=C(NCCN(C)CCNC2=CC=NC3=CC(Cl)=CC=C23)C2=C1SC1=CC=CC=C1C2=O
Martinier N
Retinoic acid Size:Solid 2 mg PF-4708671 specifically inhibits the S6K1Ceanothic acid, the A 1 homologue of betulinic acid, is isolated from Ceanothus americanus. Synthesized compounds from ceanothic acid have been shown to inhibit Epstein Barr virus early antigen activation in anti cancer research. It also demonstrates growth inhibitory effect against Streptococcus mutans, Actinomyces viscosus, Porphyromonas gingivalis, and Prevotella. Product information CAS Number: 302 79 4 Molecular Weight: 300. 44 Formula: C20H28O2
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