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Smiles: O=C(ON1C(=O)CCC1=O)C1=CC=C2COC3(C2=C1)C1=CC(F)=C(C=C1OC1=CC(=C(F)C=C31)N1CC(F)(F)C1)N1CC(F)(F)C1
InChiKey: YGIDGBAHDZEYMT-MQFIMZJJSA-N
121569-61-7
Rigosertib (100-250 nM) induces spindle abnormalities and apoptosis
Miscioscia F
TAME 0231 Smiles: O=C(ON1C(=O)CCC1=O)C1=CC=C2COC3(C2=C1)C1=CC(F)=C(C=C1OC1=CC(=C(F)C=C31)N1CC(F)(F)C1)N1CC(F)(F)C1TAME is an inhibitor of anaphase promoting complex cyclosome (APC C or APC), which binds to APC C and prevents its activation by Cdc20 and Cdh1, produces mitotic arrest[1]. Product information CAS Number: 901 47 3 Molecular Weight: 342. 41 Formula: C14H22N4O4S Synonym: Tosylarginine methyl ester N 4 Tosyl L arginine methyl ester Related CAS Number: 1784 03 8 (TAME HCl) Chemical Name: methyl (2S) 5 carbamimidamido 2 (4