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Pixantrone (dimaleate) Catalog No.:M9764-10 Formula: C6H6Cl2N2O4S2

SKU: 9378446662

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Description

Formula: C6H6Cl2N2O4S2

Smiles: C[N@@+]1(CCC2=CC(OC)=C(C=C2[C@H]1CC1=CC(OC)=C(C=C1)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N@@+]1(C)CCC2=CC(OC)=C(C=C2[C@H]1CC1=CC(OC)=C(C=C1)OC)OC

PubMed Central PMCID: PMC4264672

InChi: InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28

Pre-incubation with sodium danshensu could inhibit vessel contraction induced by phenylephrine and potassium chloride in a concentration-dependent way

Pixantrone (dimaleate) Catalog No.:M9764-10 Formula: C6H6Cl2N2O4S2Pixantrone is a synthetic, noncardiotoxic aza anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non Hodgkin lymphoma (aNHL). Product information CAS Number:

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