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Ispinesib (SB-715992) st N-oxide 14(19):3101-11

SKU: 94259548813

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Description

14(19):3101-11

Chemical Name: 4-(4-((dimethylamino)methyl)-3

acting as an androgen receptor degrader

Oksenberg D

GKT137831 reduced the hypoxia-induced increase in ROS levels and protein expression of various inflammatory mediators

Ispinesib (SB-715992) st N-oxide 14(19):3101-11Ispinesib is a synthetic small molecule, derived from quinazolinone, with antineoplastic properties. Ispinesib selectively inhibits the mitotic motor protein, kinesin spindle protein (KSP), resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and cell death in tumor cells that are actively dividing. Because KSP is not involved in nonmitotic processes, such as neuronal transport, ispinesib may be

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