Since infect puts -1/-1 counters on creatures it deals damage to, this allows Yawgmoth to act as removal so long as you have a sacrifice outlet
This is one of the best and most extreme implementations of sneak, but it takes the card from being a possible inclusion to a must-have for milling decks, and maybe even at three or four copies, too (in Standard)
That's what happens when you combine Tinker (which could get out the Jar almost immediately) with Megrim (so that your opponent would take 14 damage from a single Jar discard, assuming they could not play any cards in time)
Many of the cards force your opponents to discard cards, or support reanimation strategies
Since the card is currently only being played in just one modern deck, I personally had it in the third spot behind the best blue reactive spells in the format, Counterspell and Force of Negation, but I can see the number one spot going to the best and most efficient threat the color has to offer