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Pipamperone Size:Contact [email protected] for quotation VH298 can activate the HIF-1

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Description

VH298 can activate the HIF-1 signalling pathway by stabilizing both forms of HIF-1α in vitro

PubMed PMID: 26604805

InChi: InChI=1S/C31H36N2O/c1-21-16-22(2)30(23(3)17-21)32-31(34)33(27-11-6-4-5-7-12-27)20-24-14-15-29-26(18-24)19-25-10-8-9-13-28(25)29/h8-10

Chemical Name: N-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-1-methyl-1H-pyrazole-5-carboxamide

Mambalgin 1 TFA is a selective ASIC1a inhibitor (IC50 values are 192 and 72 nM for human ASIC1a and ASIC1a/1b dimer

Pipamperone Size:Contact [email protected] for quotation VH298 can activate the HIF-1Pipamperone (Floropipamide; McN JR 3345; R 3345) is a high affinity antagonist of 5 HT2A receptor (pKi=8. 2) and D4 receptor (pKi=8. 0) and a low affinity antagonist of D2 receptor (pKi=6. 7). Product information CAS Number: 1893 33 0 Molecular Weight: 375. 48 Formula: C21H30FN3O2 Chemical Name: 1' [4 (4 fluorophenyl) 4 oxobutyl] [1,4' bipiperidine] 4' carboxamide Smiles: NC(=O)C1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)N1CCCCC1 InChiKey: AXKPFOAXAHJUAG

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