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Clozapine N-oxide dihydrochloride - CAS# 2250025-93-3 Catalog No.:M16528-C 4-tetrahydronaphthalen-1-yl)-4

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Description

4-tetrahydronaphthalen-1-yl)-4

Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial

but exerts little effect on normal fibroblasts or endothelial cells

Pirfenidone suppresses the proinflammatory cytokine TNF-α by a translational mechanism

Formula: C91H180NO33P

Clozapine N-oxide dihydrochloride - CAS# 2250025-93-3 Catalog No.:M16528-C 4-tetrahydronaphthalen-1-yl)-4Clozapine N oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N oxide dihydrochloride can cross the blood brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist. Product information CAS Number: 2250025 93 3 Molecular

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