KU-55933 has a dose-dependent effect in inhibiting this ATM-dependent phosphorylation event with an estimated IC50 of 300 nM
Formula: C15H11ClN2O2
InChi: InChI=1S/C13H16O4/c1-8(12(14)15)7-10-3-5-11(6-4-10)9(2)13(16)17/h3-6
28-19+/t26-
InChi: InChI=1S/C43H78N10O15/c1-10-23(8)33(52-36(60)26(13-11-12-14-44)46-40(64)30(19-55)50-38(62)27(15-20(2)3)47-35(59)25(45)18-54)41(65)49-28(16-21(4)5)37(61)48-29(17-31(57)58)39(63)53-34(24(9)56)42(66)51-32(22(6)7)43(67)68/h20-30
Ganoderic acid B 21216 KU-55933 has a dose-dependent effectGanoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV 1 protease. Product information CAS Number: 81907 61 1 Molecular Weight: 516. 67 Formula: C30H44O7 Chemical Name: (2R,6R) 6 [(1R,3aR,4S,5aR,7S,9aS,11aR) 4,7 dihydroxy 3a,6,6,9a,11a pentamethyl 3,10 dioxo