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and antitumor activity in preclinical studies
filamentous actin formation and focal adhesion assembly without perturbing endogenous Cdc42 or Rac signalling
Formula: C17H16ClN3O
InChi: InChI=1S/C27H26FN3OS/c1-19-24(26(32)31-17-18-33-27(31)29-19)13-16-30-14-11-22(12-15-30)25(20-5-3-2-4-6-20)21-7-9-23(28)10-8-21/h2-10
SNIPER(CRABP) 11
H-1152 Size:Solid 10 mg and antitumor activity in preclinicalH 1152 is a selective inhibitor of ROCK. H 1152 effects on intraocular pressure and trabecular meshwork morphology of rat eyes. H 1152 is a more specific, stronger and membrane permeable inhibitor of Rho kinase with a Ki value of 1. 6 nM, but poor inhibitor of other serine threonine kinases. Product information CAS Number: 451462 58 1 Molecular Weight: 319. 42 Formula: C16H21N3O2S Synonym: H 1152 H1152 Chemical Name: 4 methyl 5 {[(2S) 2 methyl 1,4
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