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It induced a 50% loss of H3K27me3 in both EZH2 wild-type and mutant DLBCL cell lines at nM concentrations independent of EZH2 mutation status
Ziesenitz SC
Caldas-Lopes E
62 and 490 μM for PDE7A
29(42)43-5)26(40)22(39)24(31)30(4)8-14(18(35)12(3)13(30)7-16(31)47-27(23)41)45-28-21(38)20(37)19(36)15(9-33)46-28/h6
S-acetyl-PEG3-phosphonic acid ethyl ester PEG12-Tos It induced a 50% lossS acetyl PEG3 phosphonic acid ethyl ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2173125 29 4 Molecular Weight: 372. 41 Formula: C14H29O7PS Chemical Name: diethyl (13 oxo 3,6,9 trioxa 12 thiatetradecan 1 yl)phosphonate Smiles: CC(=O)SCCOCCOCCOCCP(=O)(OCC)OCC InChiKey: MVCCQMOSYHIVOE UHFFFAOYSA N InChi: InChI=1S C14H29O7PS c1 4 20 22(16,21 5 2)12 10 18 8 6 17 7 9 19 11 13 23 14(3)15 h4