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4″-di(2-imidazolin-2-yl)terephthalanilide (NSC 60339) by Sensitive and Resistant P388 Leukemia Cells
PMCID: PMC6973588
InChi: InChI=1S/C20H27N5O2/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16/h10-11
and genetic approaches
Formula: C12H17N5O4
L-Phenylalanine NE-781 4″-di(2-imidazolin-2-yl)terephthalanilide (NSC 60339) by SensitiveASTX 029 is an orally bioavailable inhibitor of the extracellular signal regulated kinases (ERK) 1 and 2, with potential antineoplastic activity. ASTX 029 inhibits ERK dependent tumor cell proliferation and survival. Product information CAS Number: 63 91 2 Molecular Weight: 165. 19 Formula: C9H11NO2 Chemical Name: (2S) 2 amino 3 phenylpropanoic acid Smiles: N[C@@H](CC1C=CC=CC=1)C(O)=O InChiKey: COLNVLDHVKWLRT QMMMGPOBSA N InChi: InChI=1S C9H11NO2 c10
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