PD-1-IN-17 ethiazide (E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a

(E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers

inhibiting PARP-mediated repair of single strand DNA breaks

Nature Chemical Biology (2016)

every day for 3 weeks) prevents SU5416-induced septal cell apoptosis

also known as COL-144 and LY573144

PD-1-IN-17 ethiazide (E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is aPD 1 IN 17 is a programmed cell death 1 (PD 1) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM. Product information CAS Number: 1673560 66 1 Molecular Weight: 374. 35 Formula: C13H22N6O7 Chemical Name: (2S) 2 ({[(1S) 1 {5 [(1S,2R) 1 amino 2 hydroxypropyl] 1,3,4 oxadiazol 2 yl} 3 carbamoylpropyl]carbamoyl}amino) 3 hydroxypropanoic acid Smiles: