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97(4):419-431
Smiles: CCO[C@@H]1OC(=O)C[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)C1=CC=C(N)C(Cl)=C1)C(C)(C)C
4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate InChI Key CDDABGWUXFFTGQ-MLSLTINKSA-N Smiles CN([C@H](C(N[C@H](C(N1C[C@@H](NC(COCCOCCOCCOCCN)=O)C[C@H]1C(N[C@@H]2CCCC3=CC=CC=C23)=O)=O)C4CCCCC4)=O)C)C(OC(C)(C)C)=O References
InChi: InChI=1S/C23H17FN6O
2-diphenylacetamide
Argatroban SK-3 inhibitor 1 97(4):419-431Argatroban is an anticoagulant that is a direct thrombin inhibitor. Argatroban was approved in 2000 for prophylaxis or treatment of thrombosis in patients with heparin induced thrombocytopenia (HIT). Argatroban is a direct thrombin inhibitor that reversibly binds to the thrombin active site. Argatroban exerts its anticoagulant effects by inhibiting thrombin catalyzed or induced reactions, including fibrin formation; activation of coagulation factors