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Cucurbitacin B Catalog No.:M12393-2 1-methyl-D-tryptophan (D-1MT)

SKU: 97255228000

4.2
USD150.00 USD199.00

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Description

1-methyl-D-tryptophan (D-1MT)

116(7):937-943

InChi: InChI=1S/C34H34N4O4

InChi: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13

Assay Drug Dev Technol

Cucurbitacin B Catalog No.:M12393-2 1-methyl-D-tryptophan (D-1MT)Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids; could repress cancer cell progression. IC50 value: Target: anticancer natural compound in vitro: Cucurbitacin B inhibited growth and modulated expression of cell cycle regulators in SHSY5Y cells. At the molecular level, we found that Cucurbitacin B inhibited AKT signaling activation through up regulation of PTEN. CuB induced apoptosis of A549 cells in a concentration

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