Bis-PEG1-acid jor) Smiles: CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O

Smiles: CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O

InChi: InChI=1S/C16H16N6/c1-2-7-17-15-5-6-16-18-10-14(22(16)21-15)11-3-4-13-12(8-11)9-19-20-13/h3-6

The mean fAUC/MIC magnitude associated with net stasis and 1-log kill endpoint are 27

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma

This agent also blocks the tyrosine kinase activity of epidermal growth factor receptor (EGFR)

Bis-PEG1-acid jor) Smiles: CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=OBis PEG1 acid is a PEG based PROTAC linker can be used in the synthesis of PROTACs. Product information CAS Number: 5961 83 1 Molecular Weight: 162. 14 Formula: C6H10O5 Chemical Name: 3 (2 carboxyethoxy)propanoic acid Smiles: OC(=O)CCOCCC(O)=O InChiKey: FOSIWKADJDNVMJ UHFFFAOYSA N InChi: InChI=1S C6H10O5 c7 5(8)1 3 11 4 2 6(9)10 h1 4H2,(H,7,8)(H,9,10) Technical Data Appearance: Solid Power Purity: 98% (or refer to the Certificate of Analysis) Shipping