WP1066 Size:Solid 2 mg Smiles: NC1=CC=CC=C1NC(=O)C1=CN=CC=N1

Smiles: NC1=CC=CC=C1NC(=O)C1=CN=CC=N1

TG101348 (SAR302503)

Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels

3'-bipyrrole]-2-carbonyl]phenol

CAS Number: 852391-15-2

WP1066 Size:Solid 2 mg Smiles: NC1=CC=CC=C1NC(=O)C1=CN=CC=N1WP1066 is a Stat3 inhibitor and JAK2 inhibitor. WP1066 is also a novel analogue of the JAK2 inhibitor AG490, in JAK2 V617F positive erythroleukemia HEL cells and in blood cells from patients with polycythemia vera. WP1066 significantly inhibited JAK2 and its downstream signal transducer and activator of transcription 3, signal transducer and activator of transcription 5, and extracellular signal regulated kinase 1 2 pathways in a dose and time