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D609 - CAS# 83373-60-8 tin-3'-sulfonate 214(2):258-64

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Description

214(2):258-64

InChiKey: LDEKQSIMHVQZJK-CAQYMETFSA-N

InChiKey: ZNOVTXRBGFNYRX-STQMWFEESA-N

reduces the secretion of the angiogenic factor tumor necrosis factor alpha by tumor-associated macrophages (TAMs)

CAS Number: 2315-02-8

D609 - CAS# 83373-60-8 tin-3'-sulfonate 214(2):258-64D 609, also known as D 609 free, is a phospholipase C inhibitor potentially for the treatment of pancreatic cancer. D 609, an inhibitor of PC PLC and sphingomyelin synthase, strongly inhibited myogenic tone and had no effect on depolarization induced contraction. D 609 appeared to act by lowering cytoplasmic Ca(2+) concentration to levels below those that activate contraction. Product information CAS Number: 83373 60 8 Molecular Weight: 266. 46

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