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Protease-Activated Receptor-3 (PAR-3) (1-6)
and MyHC expression[2]
64(17):6207-13
21(4):271-281
1%) retained significant activity against both direct tissue infection and transinfection mediated by migratory cells
BI-2852 567 Protease-Activated Receptor-3 (PAR-3) (1-6)BI 2852 is a potent inhibitor of KRAS that binds with nanomolar affinity to a pocket between switch I and II on RAS. BI 2852 blocks all GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in the low micromolar range in KRAS mutant cells. Product information CAS Number: 2375482 51 0 Molecular Weight: 516. 59 Formula: C31H28N6O2 Chemical Name: 5 hydroxy 3 (2 {[({1 [(1 methyl 1H
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