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InChi: InChI=1S/2C7H10O7
CAS Number: 477600-75-2
Chemical Name: 5-chloro-4-(1H-indol-3-yl)-N-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidin-2-amine
13-hexaen-5-yl}-N3-[(7S)-7-(pyrrolidin-1-yl)-6
FLT3 activity is inhibited by 90% at 2 hours
Dxd 935 InChi: InChI=1S/2C7H10O7Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0. 31 M, used as a conjugated drug of HER2 targeting ADC (DS 8201a). Product information CAS Number: 1599440 33 1 Molecular Weight: 493. 48 Formula: C26H24FN3O6 Synonym: Exatecan derivative for ADC Chemical Name: N [(10S, 23S) 10 ethyl 18 fluoro 10 hydroxy 19 methyl 5, 9 dioxo 8 oxa 4, 15 diazahexacyclo[14. 7. 1. 0, . 0, . 0, . 0, ]tetracosa 1, 6(11), 12, 14,