OG-L002 - LSD1 Inhibitor. CAS# 1357302-64-7 60281 is a highly specific inhibitor

is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM)

giving growth delays in A431 xenografts exceeding 50 days following oral administration

promote PKM2 tetramer formation and prevent inhibition by phosphotyrosine signaling

apoptosis through the mitochondrial pathway

4]diazepin-6-yl)acetamide

OG-L002 - LSD1 Inhibitor. CAS# 1357302-64-7 60281 is a highly specific inhibitorOG L002, CAS No. 1357302 64 7, is a highly potent and specific inhibitor of Lysine Specific Demethylase 1 (LSD1). It inhibits LSD1 in biochemical assay with an IC50 ~20 nM, and has moderate inhibitory activity against monoamine oxidases MAO A and MAO B with IC50 ~1. 38 M and 0. 72M respectively. It potently repressed herpes simplex virus (HSV) IE gene expression, genome replication, and reactivation from latency. OG L002 suppressed primary lytic