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DREADD agonist 21 is a potent human muscarinic acetylcholine M3 receptors (hM3Dq) agonist (EC50=1
Acute (5 g/kg) and chronic (25 and 250 mg/kg) toxicology studies in uninfected mice show that
CAS Number: 63912-16-3
2'-piperidin]-16-ol hydrochloride
Formula: C35H49F2N7O4
Bomedemstat ditosylate Catalog No.:M33503-C DREADD agonist 21 is aBomedemstat, also known as IMG 7289, is a lysine specific histone demethylase 1 (LSD1) inhibitor with antineoplastic activity. Bomedemstat may be useful in the treatment of acute myeloid leukaemia, myelodysplastic syndrome, and Myelofibrosis. IMG 7289 selectively inhibited proliferation and induced apoptosis of JAK2 V617F cells by concomitantly increasing expression and methylation of p53, and, independently, the pro apoptotic factor PUMA and by
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